Facile synthesis of indolizino[3, 4, 5-ab]isoindoles by an acid-induced cyclization of 1, 2-di(1H-pyrrol-2-yl)benzenes. Issue 41 (7th October 2015)

• Record Type: Journal Article
• Authors: Kuzuhara, Daiki; Miyake, Satoshi; Moriyama, Hirotake; Tamura, Yuto; Aratani, Naoki; Yamada, Hiroko
• Is Part Of: Tetrahedron letters. Volume 56:Issue 41(2015)
• Page Start: 5564
• Page End: 5567
• Publication Date: 2015-10-07
• Subjects: Indolizino[3, 4, 5-ab]isoindoles -- Cyclization -- Acid -- 1, 2-Di(1H-pyrrol-2-yl)benzene -- Fluorescence; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.08.044
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: The new synthetic method of indolizino[3, 4, 5- ab ]isoindoles (INIs) by an acid-induced intramolecular cyclization of 1, 2-di(1 H -pyrrol-2-yl)benzenes has been developed. This protocol can be applied to the preparation of INI derivatives with electron-donating and -withdrawing groups as well as azaINIs.