Identification of a quorum sensing pheromone posttranslationally farnesylated at the internal tryptophan residue from Bacillus subtilis subsp. natto. Issue 10 (3rd October 2015)

• Record Type: Journal Article
• Authors: Hayashi, Shunsuke; Usami, Syohei; Nakamura, Yuta; Ozaki, Koki; Okada, Masahiro
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 79:Issue 10(2015)
• Page Start: 1567
• Page End: 1569
• Publication Date: 2015-10-03
• Subjects: Bacillus subtilis -- isoprenylation -- posttranslational modification -- quorum sensing -- tryptophan; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2015.1032884
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: Bacillus subtilis subsp. natto produces poly-γ-glutamic acid under the control of quorum sensing. We identified ComXnatto pheromone as the quorum-sensing pheromone with an amino acid sequence of Lys-Trp-Pro-Pro-Ile-Glu and the tryptophan residue posttranslationally modified by a farnesyl group. ComXnatto pheromone is unique in the sense that the 5th tryptophan residue from the C-terminal is farnesylated.