Daily oral intake of β-cryptoxanthin ameliorates neuropathic pain. Issue 5 (4th May 2017)

• Record Type: Journal Article
• Authors: Park, Gyujin; Horie, Tetsuhiro; Iezaki, Takashi; Okamoto, Maika; Fukasawa, Kazuya; Kanayama, Takashi; Ozaki, Kakeru; Onishi, Yuki; Sugiura, Minoru; Hinoi, Eiichi
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 81:Issue 5(2017)
• Page Start: 1014
• Page End: 1017
• Publication Date: 2017-05-04
• Subjects: neuropathic pain -- β-cryptoxanthin -- allodynia; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2017.1280661
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: β-cryptoxanthin, a xanthophyll carotenoid, exerts preventive effects on various lifestyle-related diseases. Here, we found that daily oral administration of β-cryptoxanthin significantly ameliorated the development of tactile allodynia following spinal nerve injury but was ineffective in mechanical allodynia in an inflammatory pain model in mice. Our results suggest that β-cryptoxanthin supplementation would be beneficial for the prophylaxis of neuropathic pain.