Isolation of diploid baker's yeast capable of strongly activating immune cells and analyses of the cell wall structure. Issue 5 (4th May 2014)

• Record Type: Journal Article
• Authors: Takada, Yuki; Mizobuchi, Ayano; Kato, Takayuki; Kasahara, Emiko; Ito, Chinatsu; Watanabe, Hajime; Kanzaki, Ken; Kitagawa, Seiichi; Tachibana, Taro; Azuma, Masayuki
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 78:Issue 5(2014)
• Page Start: 911
• Page End: 915
• Publication Date: 2014-05-04
• Subjects: yeast -- β-glucan -- mannan -- macrophage -- mononuclear cells; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2014.917259
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: Diploid baker's yeast capable of strongly activating a mouse macrophage was constructed based on haploid mutant AQ-37 obtained previously. The obtained strain BQ-55 activated also human immune cells. To clarify a factor for the activation, the cell wall structure, especially the β-glucan structure, was analyzed, suggesting that the length of branching, β-1, 6-glucan, may be one of the factors.