A new sarasinoside congener, sarasinoside M2, from a marine sponge collected in the Solomon Islands. Issue 2 (1st February 2017)

• Record Type: Journal Article
• Authors: Puilingi, Clyde Gorapava; Kudo, Yuta; Cho, Yuko; Konoki, Keiichi; Yotsu-Yamashita, Mari
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 81:Issue 2(2017)
• Page Start: 222
• Page End: 225
• Publication Date: 2017-02-01
• Subjects: sarasinoside M2 -- cytotoxicity -- MS/MS -- marine sponge -- saponin; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2016.1246172
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: A new sarasinoside congener (sarasinoside M2 ) and known sarasinoside B1 were obtained from a marine sponge . Sarasinoside M2 was suggested to have the same aglycon as sarasinoside M although the internal glucose in its sugar moiety is replaced by xylose. Sarasinosides B1 and M2 showed moderate cytotoxicity (approximate IC50 5–18 μM) toward Neuro-2a and HepG2 cell lines.