Fractured epicardial lead in paediatric patients: can they be safely repaired?. (19th May 2022)

• Record Type: Journal Article
• Authors: Silvetti, M S; Campisi, M; Silvetti, G; Tamburri, I; Saputo, FA; Battista, V; Albanese, S; Drago, F
• Is Part Of: Europace. Volume 24:Supplement 1(2022)
• Publication Date: 2022-05-19
• Subjects: Arrhythmia -- Treatment -- Periodicals; Cardiac pacing -- Periodicals; Catheter ablation -- Periodicals; Heart -- Physiology -- Periodicals; Electrophysiology -- Periodicals; 617.4120645
• DOI: 10.1093/europace/euac053.423
• Languages: English
• ISSNs: 1099-5129

Abstract

Abstract: Funding Acknowledgements: Type of funding sources: None. Background/Introduction: Before bipolar epicardial leads became widely available and used by heart surgeons, unipolar epicardial leads were frequently implanted in small children requiring permanent pacing. Main complications are lead fractures causing pacing/sensing defect. Therefore, patients should undergo new epicardial or endocardial lead implantation with relevant procedural risks, especially in complex congenital heart disease (CHD). Proximal fractures, close to the generator, may be repaired using a dedicated Unipolar Lead Adapter and Extension, with reduced operative risks. Purpose of the study is the retrospective analysis of the outcome of the repair of unipolar epicardial leads in young patients (pts) in a single tertiary paediatric center. Methods: Consecutive patients with proximal fracture underwent a trial of lead repair using the lead adapter/extension, during general anaesthesia, cefuroxime antibiotic profilaxis, from 2004 to 2020. Lead data (threshold, sensing, impedance) were compared before and after the repair procedure. Results: 18 patients with CHD (12pts, 10 of whom complex, 6 post-Fontan) or normal structural heart (6pts), who underwent pacemaker implantation at 2.5 (0.7-5.8)years of age for congenital/postoperative atrioventricular block (11pts) and sinus node dysfunction (7pts), showed lead (7 atrial, 11 ventricular) fractures after chronic pacing. At 13 (8-17)years of age, all leads were successfully repaired without any complications. Follow-up was 4 (2-6)years. Four pts (22%) showed again fractures of the repaired lead, after 1 month, 1and 3 years (2pts). Electrical lead parameters are shown in table 1: there were not significant differences between consecutive time of controls, also in the atrial and ventricular lead subgroups. Table 1.-------------------Pre-repair;--intraprocedural;---1 month;----------1 year;-------------4 years. Threshold (V/0.4 ms):--1.1 (0.7-1.4);--1.0 (0.8-1.6);-------1.2 (0.9-1.5);-----1.2 (0.9-2.1);-------1.5 (1.1-1.8). Sensing (mV):--------- 7 (2.4-12);------5.4 (1.3-15);-------4 (1.5-11);----------5 (1.6-12);---------3 (2-10). Impedance (ohm): 343 (289-407);---350 (246-415);--346 (250-432);--374 (250-589);--362 (220-470). Conclusion: The repair of fractured unipolar epicardial leads in young patients is a safe and effective procedure, with few complications during follow-up. Effective repair can delay more aggressive procedures.