P70 ESPERIENZA CLINICA DELLE PRIME 41 PROCEDURE DI LITOTRISSIA INTRACORONARICA IN UN CATH–LAB ITALIANO. (18th May 2022)

• Record Type: Journal Article
• Authors: Barbero, U; Pavani, M; Moncalvo, C; Ajassa, M; De Benedictis, M
• Is Part Of: European heart journal supplements. Volume 24(2022)Supplement C
• Publication Date: 2022-05-18
• Subjects: Cardiology -- Periodicals; Cardiology -- Europe -- Periodicals; 616.12005
• DOI: 10.1093/eurheartj/suac012.068
• Languages: English
• ISSNs: 1520-765X

Abstract

Abstract: Introduction: Stent under expansion is one of the main predictors of percutaneous coronary intervention (PCI) failure, being a trigger for both in–stent restenosis and stent thrombosis, with their obvious clinical impact. Among the main causes of stent failure, the presence of a severely calcified lesion is the most frequent and dangerous. Correct recognition and preparation of target lesion are therefore mandatory before stenting. Methods: We enrolled all the patients treated with angioplasty and IVL (Shockwave Medical Inc, Santa Clara, USA) from October 2020 to October 2021 in our cath lab. Each patient signed informed consent. Results: We enrolled 35 patients (with 41 lesions treated with IVL). Mean age was 73 years old, 29 were males (82%). Clinical characteristics are shown in the table. Twenty–one lesions (50%) were treated up–stream before stenting, 6 (16%) were bail–out IVL for inadequate stent expansion after post–dilation and 14 (37%) were in–stent restenosis with evidence of stent under–expansion because of the high burden of calcium. Fifty–four per cent of patients were treated in the context of Acute Coronary Syndrome (ACS). Seventy–three per cent of patient had three–vessel disease. The majority of procedure were done through radial access (74%) and 79% of the stenosis was prepared with NC balloons (at least 2.5 mm diameter) before deployment of the IVL balloon; in 2 case IVL was done after rotational atherectomy. Intravascular ultrasound (IVUS) guidance was used in in 15 pts. Two balloon were broken during lithotripsy. In 26 of 41 stenosis (63%) IVL delivery was obtained on a single wire, while 11 required buddy–wire (of whom 8 required child–in–mother technique to obtain adequate support for delivery). We had two major complications: 1 case of ventricular fibrillation (in a patients with recent myocardial infarction and severe reduction of ejection fraction, and 1 case of perforation at the time of inflation of the NC balloon after IVL easily treated with positioning of a covered stent which was easily delivered thanks to the previous IVL treatment). Conclusion: IVL is a safe and all–around technique for treatment of severely calcified lesion in different clinical contexts from stable coronary artery disease to ACS, useful for upstream calcium treatment as well as bail–out stent optimization and correction of under expansion in calcified in–stent restenosis.