Intraoperative imaging techniques for glioma surgery. (August 2017)

• Record Type: Journal Article
• Authors: Garzon-Muvdi, Tomas; Kut, Carmen; Li, Xingde; Chaichana, Kaisorn L
• Is Part Of: Future oncology. Volume 13:Number 19(2017)
• Page Start: 1731
• Page End: 1745
• Publication Date: 2017-08
• Subjects: fluorescence-guided resection -- intraoperative MRI -- intraoperative ultrasound -- optical coherence tomography -- Raman spectroscopy; Oncology -- Periodicals; 616.99405
• DOI: 10.2217/fon-2017-0092
• Languages: English
• ISSNs: 1479-6694

Abstract

Gliomas are CNS neoplasms that infiltrate the surrounding brain parenchyma, complicating their treatment. Tools that increase extent of resection while preventing neurological deficit are essential to improve prognosis of patients diagnosed with gliomas. Tools such as intraoperative MRI, ultrasound and fluorescence-guided microsurgery have been used in the surgical resection of CNS gliomas with the goal of maximizing extent of resection to improve patient outcomes. In addition, emerging experimental techniques, for example, optical coherence tomography and Raman spectroscopy are promising techniques which could 1 day add to the increasing armamentarium used in the surgical resection of CNS gliomas. Here, we present the potential advantages and limitations of these imaging techniques for the purposes of identifying gliomas in the operating room.