Eribulin as an effective monotherapy in a chemo-pretreated woman with metastatic breast cancer: a case report. (April 2017)

• Record Type: Journal Article
• Authors: Caputo, Roberta; Cianniello, Daniela; De Laurentiis, Michelino
• Is Part Of: Future oncology. Volume 13(2017)Supplement 11
• Page Start: 45
• Page End: 50
• Publication Date: 2017-04
• Subjects: anthracyclines -- eribulin -- metastatic breast cancer -- taxanes; Oncology -- Periodicals; 616.99405
• DOI: 10.2217/fon-2016-0516
• Languages: English
• ISSNs: 1479-6694

Abstract

Anthracycline- or taxane-based regimens are commonly used in the treatment of breast cancer, often in the (neo)adjuvant and first-line metastatic settings. However, to date, there is no single accepted standard of care after failure of these cytotoxic agents. Following the promising results obtained in the Phase III EMBRACE study, eribulin mesylate was approved for the treatment of metastatic breast cancer patients after progression with anthracyclines and taxanes unless contraindications. This case report describes a chemo-pretreated woman with important pleural effusion, nodal, locoregional involvement from breast cancer who had a disease response after treatment with eribulin in second line. This case underlines how this well-tolerated monochemotherapy may be able to obtain a prolonged disease control and a good clinical outcome.