Determination of Glycerin from a Marketed Personal Care Product Using Gas Chromatography. (9th February 2015)

• Record Type: Journal Article
• Authors: De, Amit Kumar; Chowdhury, Partha Pratim; Chattopadhyay, Shyama Prasad
• Other Names: Bonferoni Maria Cristina Academic Editor.
• Is Part Of: Advances in pharmaceutics. Volume 2015(2015)
• Publication Date: 2015-02-09
• Subjects: Pharmacology -- Periodicals; Drugs -- Dosage forms -- Periodicals; Solid dosage forms; Dosage Forms; Periodicals; 615.19
• DOI: 10.1155/2015/567032
• Languages: English
• ISSNs: 2356-6841

Abstract

Abstract : The current study presents a packed column gas chromatographic technique for the estimation of glycerin using a flame ionization detector from a marketed hair tonic in presence of resorcinol, ethanol, biotin, keratin hydrolysate, undecylenic acid alkylolamide (hyalkyl HBU), D-biotin, nicotinic acid, and polyvinylpyrrolidone. The validation studies show the proposed method to be specific, sensitive, precise, and accurate. The method is found to be linear in the concentration range 1.25 mg/mL to 10.02 mg/mL with r 2 value 0.99. The limit of detection and the limit of quantitation were 0.01 mg/mL and 0.05 mg/mL, respectively. The method does not involve any complex sample preparation procedure and is therefore suitable for regular analysis of glycerin from marketed hair tonic.