Encapsulation artocarpanone and ascorbic acid in O/W microemulsions: Preparation, characterization, and antibrowning effects in apple juice. (1st February 2016) - Dong, Xue
Highlights: Pseudo-ternary phase diagram was constructed to optimize microemulsion formation. ArtoME and Arto + VcME were developed and characterized. ArtoME and Arto + VcME were stable under accelerated and long-term storage. Incorporating Vc into ArtoME improved the stability of Arto in long-term storage. Arto + VcME showed strong antibrowning effects on apple juices at room temperature. Abstract: The aim of this study is to improve artocarpanone solubility by developing an O/W microemulsion with the evaluation of its antibrowning effects. The chemical and physical stabilities as well as antibrowning effects in apple juice were also evaluated. The formulation of artocarpanone microemulsion consisted of 4% w/w of ethyl butyrate, 10.67% w/w of Tween 80, 5.33% w/w of polyethylene glycol 400, and 80% w/w of water, with a maximum solubility of artocarpanone up to 10.54 ± 0.01 mg/mL, at least 3000-folds increase in solubility compared that in water. Encapsulating artocarpanone and ascorbic acid (VC ) into microemulsion simultaneously decreased modest artocarpanone solubility whereas improving its stability in long-term storage. Blank, artocarpanone and artocarpanone-Vc-loaded microemulsions demonstrated steadily during accelerated and long-term storage. Artocarpanone-Vc-loaded microemulsion showed strong antibrowning effects in apple juice at room temperature in 24 h, suggesting that artocarpanone-Vc-loaded microemulsion is a good antibrowning agent for apple juices.