A phthalimide-based fluorescent probe for thiophenol detection in water samples and living cells with a large Stokes shift. Issue 43 (28th October 2015)

• Record Type: Journal Article
• Authors: Liu, Xingjiang; Yang, Liu; Gao, Li; Chen, Wenqiang; Qi, Fengpei; Song, Xiangzhi
• Is Part Of: Tetrahedron. Volume 71:Issue 43(2015)
• Page Start: 8285
• Page End: 8289
• Publication Date: 2015-10-28
• Subjects: Fluorescent probe -- Phthalimide -- Photo-induced electron transfer (PET) -- Excited-state intramolecular proton transfer (ESIPT) -- Thiophenol; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2015.08.074
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: A phthalimide-based fluorescent probe for the detection of thiophenol was developed based on the combination of photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT) mechanisms. This probe displays high sensitivity and good selectivity toward thiophenol with a large Stokes shift (161 nm) and a low detection limit (3.5 nM, based on S/N=3). Furthermore, the applications of this probe for quantitative detection of thiophenol in real water samples and imaging intracellular thiophenol in living cells were successfully demonstrated. Graphical abstract: