An optimized extraction technique for acetylcholinesterase inhibitors from the Camellia japonica seed cake by using response surface methodology. Issue 7 (3rd July 2014)

• Record Type: Journal Article
• Authors: Kim, Jae Kyeom; Kim, Cho Rong; Lim, Ho-Jeong; Nam, Sang Hae; Joo, Ok Soo; Shin, Dong-Hoon; Shin, Eui-Cheol
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 78:Issue 7(2014)
• Page Start: 1237
• Page End: 1241
• Publication Date: 2014-07-03
• Subjects: Camellia japonica -- camellia seed cake -- acetylcholinesterase -- Alzheimer's disease -- response surface methodology; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2014.915723
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: The response surface methodology (RSM) was used to optimize the extraction conditions for the acetylcholinesterase (AchE) inhibitory activity and extraction yield from Camellia japonica seed cake. Predicted values for AchE inhibition and extraction yield were 19.41 and 13.35%, respectively, which are in good agreement with the experimental values from validation, suggesting that RSM may provide a useful tool to optimization processes.