Effects of low molecular weight soybean peptide on mRNA and protein expression levels of differentiation markers in normal human epidermal keratinocytes. Issue 6 (3rd June 2014)

• Record Type: Journal Article
• Authors: Tokudome, Yoshihiro; Nakamura, Kyosuke; Hashimoto, Fumie
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 78:Issue 6(2014)
• Page Start: 1018
• Page End: 1021
• Publication Date: 2014-06-03
• Subjects: low molecular weight soybean peptide -- keratinocyte -- differentiation -- skin -- epidermis; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2014.910092
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: Low molecular weight soybean peptide (LSP) was applied to normal human epidermal keratinocytes, and the results showed a significant increase in the gene expression levels of involucrin, transglutaminase, and profilaggrin. Filaggrin protein levels were also significantly higher. It is possible that LSP has an epidermal cell differentiation-promoting effect and may be able to regulate metabolism of the epidermis.