Z-Isomers of lycopene exhibit greater liver accumulation than the all-E-isomer in mice. Issue 2 (1st February 2020)

• Record Type: Journal Article
• Authors: Honda, Masaki; Nakayama, Yuki; Nishikawa, Sho; Tsuda, Takanori
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 84:Issue 2(2020)
• Page Start: 428
• Page End: 431
• Publication Date: 2020-02-01
• Subjects: Carotenoid -- E/Z-isomerization -- bioavailability -- liver accumulation; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2019.1677144
• Languages: English
• ISSNs: 0916-8451

Abstract

ABSTRACT: The effect of oral administration of all- E -isomer-rich and Z -isomer-rich lycopene on liver accumulation in mice was investigated. When a diet rich in the Z -isomers was administered for 4 weeks, the total lycopene concentration in the liver was more than 3 times higher than that of all- E -isomer administration. This result clearly indicates that lycopene Z -isomers show greater bioavailability and/or liver accumulation than the all- E -isomer in mice.