Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation. Issue 7 (3rd July 2017)

• Record Type: Journal Article
• Authors: Yamashita, Yasunobu; Biard, Alan; Hanaya, Kengo; Shoji, Mitsuru; Sugai, Takeshi
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 81:Issue 7(2017)
• Page Start: 1279
• Page End: 1284
• Publication Date: 2017-07-03
• Subjects: wogonin -- astringin -- site-selective acetylation -- site-selective deacetylation -- hydroxylation; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2017.1303362
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: Wogonin and astringin were synthesized from inexpensive chrysin and piceid in short steps. The key feature of these syntheses is site-selective transformation. The target molecules were obtained in 27 and 62% yields from the starting materials, respectively. Graphical abstract: : wogonin and astringin were synthesized from chrysin and piceid in short steps, based on site-selective transformations of acetyl protective groups.