Desmodianone H and uncinanone B, potential tyrosinase inhibitors obtained from Lespedeza maximowiczii by using bioactivity-guided isolation. Issue 6 (3rd June 2014)

• Record Type: Journal Article
• Authors: Heo, Do Yeon; Kim, Young Mi; Lee, Joongku; Park, Sang-Hong; Kim, Jinki; Park, Hye Min; Lee, Choong Hwan
• Is Part Of: Bioscience, biotechnology, and biochemistry. Volume 78:Issue 6(2014)
• Page Start: 943
• Page End: 945
• Publication Date: 2014-06-03
• Subjects: Lespedeza maximowiczii -- desmodianone H -- uncinanone B -- tyrosinase inhibition activity; Biotechnology -- Periodicals; Biochemistry -- Periodicals; 660.6
• DOI: 10.1080/09168451.2014.905180
• Languages: English
• ISSNs: 0916-8451

Abstract

Abstract: A new bioactive compound, namely desmodianone H (1), and another known compound uncinanone B (2) were first isolated using bioactivity-guided isolation from the leaves of Lespedeza maximowiczii and structures were elucidated by comprehensive analysis of their nuclear magnetic resonance and mass spectrometry data. Compounds 1 and 2 exhibited strong inhibitory effects on mushroom tyrosinase activity.