Sleep's role in memory reconsolidation. (June 2020)

• Record Type: Journal Article
• Authors: Simon, Katharine C; Gómez, Rebecca L; Nadel, Lynn
• Is Part Of: Current opinion in behavioral sciences. Volume 33(2020)
• Page Start: 132
• Page End: 137
• Publication Date: 2020-06
• Subjects: Psychology -- Periodicals; 150.5
• DOI: 10.1016/j.cobeha.2020.04.001
• Languages: English
• ISSNs: 2352-1546

Abstract

Highlights: Consolidated memories can be reactivated and altered via reconsolidation. Sleep is critical for restabilizing reconsolidated memories. Reconsolidation may be engineered in sleep using targeted memory reactivation. Abstract : Processes occurring during sleep contribute critically to the stabilization of new learning for long-term retention. Previously consolidated memory traces can be reactivated rendering memories labile again, and vulnerable to disruption or alteration. Across the phases of reactivation, modification, and re-consolidation, processing during sleep may play an essential role in restabilizing the transformed memory. We discuss recent research assessing the impact of sleep on reactivated memories potentially undergoing reconsolidation. We further evaluate targeted memory reactivation, an intervention that can directly engineer reconsolidation during sleep. Although sleep may play a role in restabilizing newly-modified memories, much remains to be explored before we fully understand the supporting mechanisms.