Association between anthropometric indices of obesity and risk of cardiovascular disease in Japanese men. Issue 1 (21st November 2019)

• Record Type: Journal Article
• Authors: Xiang, Mi; Hu, Huanhuan; Imai, Teppei; Nishihara, Akiko; Sasaki, Naoko; Ogasawara, Takayuki; Hori, Ai; Nakagawa, Tohru; Yamamoto, Shuichiro; Honda, Toru; Okazaki, Hiroko; Uehara, Akihiko; Yamamoto, Makoto; Miyamoto, Toshiaki; Kochi, Takeshi; Eguchi, Masafumi; Murakami, Taizo; Shimizu, Makiko; Tomita, Kentaro; Nagahama, Satsue; Nanri, Akiko; Konishi, Maki; Akter, Shamima; Kuwahara, Keisuke; Kashino, Ikuko; Yamaguchi, Miwa; Kabe, Isamu; Mizoue, Tetsuya; Kunugita, Naoki; Dohi, Seitaro
• Other Names: Inoue Y investigator.; Fukunaga A investigator.; Islam Z investigator.; Kurotani K investigator.; Watanabe Y investigator.; Ogasawara T investigator.; Hasegawa M investigator.; Shirozu M investigator.; Shimizu C investigator.; Gonmori N investigator.; Ogasawara A investigator.; Kato N investigator.; Tomizawa A investigator.; Sone T investigator.; Fukasawa K investigator.; Nishiura C investigator.; Kinugawa C investigator.; Kuroda R investigator.; Yamamoto K investigator.; Ohtsu M investigator.; Sakamoto N investigator.; Osaki Y investigator.; Totsuzaki T investigator.; Endo M investigator.; Itoh T investigator.; Kawashima M investigator.; Masuda M investigator.; Kitahara K investigator.; Yokoya T investigator.; Fukai K investigator.; Odagami K investigator.; Kobayashi Y investigator.;
• Is Part Of: Journal of occupational health. Volume 62:Issue 1(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-11-21
• Subjects: body mass index -- cardiovascular disease -- waist circumference -- waist‐to‐height ratio; Medicine, Industrial -- Periodicals; Industrial hygiene -- Periodicals; Medicine, Industrial; Occupational Diseases; Occupational Exposure; Occupational Health; Occupational Medicine; Periodicals; Periodical; Electronic journals; 613.62
• DOI: 10.1002/1348-9585.12098
• Languages: English
• ISSNs: 1341-9145

Abstract

Abstract: Objectives: We aimed to compare the association of body mass index (BMI), waist circumference (WC), and waist‐to‐height ratio (WHtR) with risk of cardiovascular disease (CVD) among middle‐aged working Japanese men. Methods: A nested case‐control study was performed among middle‐aged male employees who underwent periodic health checkup. A total of 241 CVD cases were identified and matched individually on age, gender, and worksite with 1205 controls. Data on BMI, WC, WHtR, smoking, hypertension, diabetes, and dyslipidemia collected at 4 years before the event/index date were retrieved. Associations between BMI, WC, WHtR, and CVD risk were assessed by using conditional logistic regression models. Results: The strength of the association of BMI, WC, and WHtR with CVD risk was similar. The smoking‐adjusted odds ratio (95% confidence interval) for CVD was 1.60 (1.38‐1.85), 1.53 (1.33‐1.78), and 1.56 (1.35‐1.81) for a 1 SD unit increase in BMI, WC, and WHtR respectively. After further adjustment for hypertension, diabetes, and dyslipidemia, these associations were attenuated but remained statistically significant. Conclusions: Measures of general (BMI) and abdominal (WC and WHtR) obesity were similarly associated with CVD in middle‐aged Japanese men.