Outpatient COVID‐19 surveillance testing in orthotopic heart transplant recipients. Issue 12 (19th October 2020)

• Record Type: Journal Article
• Authors: Carey, Sandra A.; Afzal, Aasim; Jamil, Aayla; Williams, Sarah; Gottlieb, Robert L.
• Is Part Of: Clinical transplantation. Volume 34:Issue 12(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-10-19
• Subjects: cardiac transplantation -- clinical decision‐making -- complication: infectious -- infection and infectious agents -- risk assessment/risk stratification -- viral; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ctr.14105
• Languages: English
• ISSNs: 0902-0063

Abstract

Abstract: COVID‐19 case fatality rate in the United States is currently reported at 4.8% based on the confirmed cases of COVID‐19. However, there are conflicting reports of estimated deaths in the post‐cardiac transplantation patient population associated with COVID‐19. Methods: Observational, retrospective analysis of a large cohort of post Orthotopic Heart Transplantation (OHT) patients in a high volume heart transplantation program in Dallas, Texas underwent outpatient COVID‐19 screening and testing for both SARS‐CoV‐2 nasopharyngeal RT‐PCR and anti‐SARS‐CoV2 IgG serology as a result of a clinic protocol to facilitate re‐opening of face‐to‐face outpatient clinical visits. Results: The full outpatient cohort tested at time of their clinic visit tested negative for COVID‐19 by nasopharyngeal RT‐PCR. Only 2 patients tested seropositive for anti‐SARS‐COV2 IgG. Five positive inpatient cases were also identified and all, but one recovered. Conclusion: A COVID‐19 surveillance protocol can be easily instituted in this high‐risk population and facilitate safe transplant clinic operation. As the cases and prevalence increase across the United States, further strategies will need to be developed to determine the best course of action to help manage this select population while minimizing their exposure to the ongoing pandemic.