Maladaptive neurovisceral interactions in patients with Internet gaming disorder: A study of heart rate variability and functional neural connectivity using the graph theory approach. (12th July 2019)

• Record Type: Journal Article
• Authors: Park, Su Mi; Lee, Ji Yoon; Choi, A Ruem; Kim, Bo Mi; Chung, Sun Ju; Park, Minkyung; Kim, In Young; Park, Jinsick; Choi, Jeongbong; Hong, Sung Jun; Choi, Jung‐Seok
• Is Part Of: Addiction biology. Volume 25:Number 4(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-07-12
• Subjects: autonomic nervous system -- functional connectivity -- heart rate variability -- Internet gaming disorder -- neurovisceral integration; Substance abuse -- Periodicals; Substance abuse -- Physiological aspects -- Periodicals; Substance-Related Disorders -- periodicals; 616.86
• DOI: 10.1111/adb.12805
• Languages: English
• ISSNs: 1355-6215

Abstract

Abstract: Heart rate variability (HRV) can be used to represent the regulatory adaptive system and is a proxy for neurovisceral integration. Consistent with the view that, like other addictions, Internet gaming disorder (IGD) involves disrupted regulatory function, the present study hypothesized that IGD patients would show (a) decreased HRV, (b) ineffective functional neural connectivity, and (c) differential patterns of association between HRV and functional neural connectivity relative to healthy controls (HCs). The present study included 111 young adults (53 IGD patients and 58 age‐ and sex‐matched HCs) who underwent simultaneous recordings with an electrocardiogram and electroencephalogram during a resting state. Heart rate (HR), HRV, and functional neural connectivity were calculated using the graph theory approach. Compared with the HCs, the IGD patients exhibited elevated HR and decreased HRV based on the high frequency (HF), which reflects suppression of parasympathetic and/or vagal tone. The IGD patients also exhibited a heightened theta band characteristic path length (CPL) compared with HCs, indicating decreased efficacy of the functional network. Furthermore, IGD patients exhibited negative correlations between the standard deviation of the normal‐to‐normal interval index (SDNNi) and theta and delta CPL values, which were not observed in HCs. In conclusion, the present findings suggest that IGD patients might have maladaptive brain‐body integration features involving disruptions of the autonomic nervous system and brain function. Abstract : Compared to healthy controls (HCs), Internetgaming disorder (IGD) patients showed decreased heart ratevariability (HRV) as represented by the high frequency (HF) and heightenedtheta band characteristic path length (CPL), indicating decreased efficacyof the functional network. IGD patients exhibited negative correlationsbetween the standard deviation of the normal‐to‐normal interval index(SDNNi) and theta and delta CPL. The findings suggest that IGD patients havemaladaptive brain–body integration features involving disruptions ofthe autonomic nervous system and brain function.