PICU admission and complications following adenotonsillectomies in pediatric patients: A retrospective cohort study. (July 2022)

• Record Type: Journal Article
• Authors: Than, Kathleen; Mun-Price, Connie; Klein, Margaret J.; Ross, Patrick A.; Gomez, Gabriel; Nagoshi, Makoto
• Is Part Of: International journal of pediatric otorhinolaryngology. Volume 158(2022)
• Publication Date: 2022-07
• Subjects: Pediatric -- Severe OSA -- Adenotonsillectomy -- PICU admission; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Oto-rhino-laryngologie -- Périodiques; Pédiatrie -- Périodiques; 618.9209751
• DOI: 10.1016/j.ijporl.2022.111166
• Languages: English
• ISSNs: 0165-5876

Abstract

Abstract: Background: Children with obstructive sleep apnea (OSA) have higher risks of post-operative respiratory complication after adenotonsillectomy. However, there is no clinical standard criteria for pediatric intensive care unit (PICU) admission following adenotonsillectomy. The purpose of this study was to identify perioperative risk factors associated with the need for PICU level care after adenotonsillectomy. Methods: We performed a retrospective chart review of children with severe OSA (apnea hypopnea index on polysomnography; AHI ≥10) and/or post-operative PICU admission at a tertiary academic center from May 2010 to September 2018. We collected demographics, pre-existing comorbidities, perioperative medications, and post-operative complications. We defined a primary outcome as escalation of airway management while in the PICU or PICU stay >48 h. Airway escalation included the need for an invasive airway, new CPAP application, increased CPAP setting, or increased supplemental oxygen. Results: Analysis included 278 children with severe OSA and/or PICU admission. Median age was 6.6 years old; 181 (65%) were admitted to the PICU, and 60 (21.5%) had the composite outcome of escalation of airway management or prolonged stay. In patients with an escalation of airway management, 28 needed intubation or mechanical ventilation. Multivariable logistic regression showed intraoperative respiratory complications, polysomnography (PSG) peak end-tidal CO2 (EtCO2 ) reading >60 mmHg, and the presence of neuromuscular disease as significant associated factors for escalation of airway management or prolonged PICU stay ( P values < 0.01; odd ratios 3.4, 5.3, and 5.4, respectively). Conclusion: For children following adenotonsillectomy, PSG EtCO2 ≥ 60%, preexisting neuromuscular disease, and intraoperative complications (hypoxia, difficult airway, etc.) were independently associated with escalation of airway management or prolonged stay. AHI was not an independent predictor for PICU complication. We concluded factors should be considered for PICU admission in addition to AHI. Highlights: a. Questions: There is no clinical standard for PICU admission after adenotonsillectomy for children with severe OSA. Findings: PSG EtCO2, neuromuscular dz and complication in OR were associated with airway management escalation in PICU. Meanings: As independent predictors, these factors should be considered along with AHI for a PICU admission.