Hand-assisted laparoscopic versus laparoscopic-assisted radical gastrectomy in the treatment of advanced distal gastric cancer: final results of a single-center randomized study. Issue 7 (July 2022)

• Record Type: Journal Article
• Authors: Luo, Guode; Xiang, Qin; Wang, Xiaohua; Li, Yajiao; Cao, Yongkuan; Gong, Jiaqing; Li, Yunming
• Is Part Of: Journal of international medical research. Volume 50:Issue 7(2022)
• Publication Date: 2022-07
• Subjects: Hand-assisted laparoscopic surgery -- laparoscopic-assisted surgery -- overall survival -- disease-free survival -- advanced gastric cancer -- gastric cancer prognosis; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/03000605221109361
• Languages: English
• ISSNs: 0300-0605

Abstract

Objective: To compare the results and 5- and 8-year overall survival (OS) and disease-free survival (DFS) of hand-assisted laparoscopic surgery (HALS) and laparoscopic-assisted surgery (LAS) in radical gastrectomy for advanced distal gastric cancer. Methods: A total of 124 patients admitted to our institution from May 2009 to April 2013 were randomly divided into a HALS group (n = 62) and a LAS group (n = 62). Postoperatively, 110 patients were followed for 5 and 8 years, and 14 patients were lost to follow-up. The 5- and 8-year OS and DFS rates of the groups were compared and analyzed. Results: The 5- and 8-year OS rates, respectively, were 38.8% and 19.4% in the HALS group and 38.3% and 15.3% in the LAS group (log-rank test, χ 2 = 0.250). The 5- and 8-year DFS rates, respectively, were 23.1% and 10.6% in the HALS group and 19.3% and 11.6% in the LAS group (log-rank test, χ 2 = 0.109). No significant differences were found. Conclusion: Compared with LAS, HALS radical gastrectomy for advanced distal gastric cancer had a lower conversion rate to open surgery, shorter surgical duration, and more thorough dissection of lymph nodes; 5- and 8-year OS and DFS rates were similar to those with LAS.