Spontaneous splenic rupture from indeterminate dendritic cell proliferation: a case report. Issue 6 (7th June 2022)

• Record Type: Journal Article
• Authors: Iqbal, Shaikh B; Chittal, Abhinandan R; Rao, Shiavax J; Lakra, Pallavi; Bhansali, Deepty; Pyrgos, George
• Is Part Of: Journal of surgical case reports. Volume 2022:Issue 6(2022)
• Publication Date: 2022-06-07
• Subjects: Surgery -- Periodicals; Surgery -- Case studies -- Periodicals; 617.005
• DOI: 10.1093/jscr/rjac211
• Languages: English
• ISSNs: 2042-8812

Abstract

Abstract: Spontaneous splenic rupture is a rare and life-threatening phenomenon, usually associated with an underlying infectious, inflammatory, hematological, neoplastic or rheumatologic condition. Indeterminate cell tumor is a rare neoplastic dendritic cell disorder that is poorly understood but shares immunophenotypic markers for Langerhans cells without Birbeck granules. A 73-year-old man presented with upper abdominal pain after an unwitnessed fall. Computed tomography angiography showed splenomegaly and a large ruptured splenic subcapsular hematoma. Intraoperative findings from an emergency laparotomy revealed a large hemoperitoneum and a ruptured spleen. Microscopic sections identified numerous, mostly poorly formed, small nodules classified as a proliferation of indeterminate dendritic cell tumors.