Correlation of Surgical Pleth Index with Stress Hormones during Propofol-Remifentanil Anaesthesia. (2nd September 2012)

• Record Type: Journal Article
• Authors: Chen, Xinzhong; Thee, Carsten; Gruenewald, Matthias; Ilies, Christoph; Höcker, Jan; Hanss, Robert; Steinfath, Markus; Bein, Berthold
• Other Names: Christensen N. J. Academic Editor.; Martin E. O. Academic Editor.
• Is Part Of: TheScientificWorldjournal. Volume 2012(2012)
• Publication Date: 2012-09-02
• Subjects: Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1100/2012/879158
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : Eighty patients undergoing elective ear-nose-throat surgery were enrolled in the present study to investigate the relationship between surgical pleth index (SPI) and stress hormones (ACTH, cortisol, epinephrine, norepinephrine) during general anaesthesia which was induced and maintained with propofol and remifentanil using a target-controlled infusion. The study concluded that the SPI had moderate correlation to the stress hormones during general anaesthesia, but no correlation during consciousness. Furthermore, SPI values were able to predict ACTH values with high sensitivity and specificity.