The Phenox Clot Retriever as Part of a Multimodal Mechanical Thrombectomy Approach in Acute Ischemic Stroke: Single Center Experience in 56 Patients. (24th April 2012)

• Record Type: Journal Article
• Authors: Prothmann, Sascha; Lockau, Hannah; Dorn, Franziska; Poppert, Holger; Förschler, Annette; Zimmer, Claus; Liebig, Thomas
• Other Names: Engelhorn Tobias Academic Editor.
• Is Part Of: TheScientificWorldjournal. Volume 2012(2012)
• Publication Date: 2012-04-24
• Subjects: Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1100/2012/190763
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : Purpose . We analyzed our experience with the phenox clot retriever as part of a multimodal mechanical thrombectomy (MTE) approach in acute ischemic stroke. Methods . 56 patients were treated by MTE with the phenox clot retriever alone or in combination with other modalities. Results . Overall we achieved TICI 2b/3 reperfusion rates of 61, 9%. In multimodally treated patients we achieved reperfusion rates of 72, 8%. There were 3 (5, 5%) severe adverse events, all symptomatic intracranial hemorrhages. The mean angio to reperfusion times (ART) were 74 minutes for phenox-only procedures and 51 minutes for multimodal procedures. A chronological analysis showed a reduction of ART from 70, 5 to 49, 4 minutes and an increase of TICI 2b/3 recanalizations from 53, 8% to 81, 8%. Throughout the observation period there was a significant shift towards multimodal procedures with simultaneous increase of TICI 2b/3 reperfusions. Both effects are partially attributable to our institutional learning curve. NIHSS improvement could be seen in 54% (n = 28 ) overall and in 73% (n = 15 ) of MCA recanalizations. Conclusions . The phenox clot retriever is a safe and effective tool for MTE in acute stroke patients, with faster and better reperfusion results when used as part of a multimodal strategy. Clinical improvement is more frequent in MCA recanalizations.