Failure of multiplex meningitis/encephalitis (ME) NAT during cryptococcal meningitis in solid organ recipients. Issue 4 (11th June 2020) - Pilmis, Benoit
Abstract: Cryptococcal meningitis is a severe cause of central nervous system infections among immunocompromised solid organ transplant (SOT) patients. While new diagnostic methods as multiplex meningitis/encephalitis (ME) NAT (nucleic acid test) are increasingly used as a first‐line tool in hospital practice, data in HIV‐negative patients including SOT remain scarce. We report here false‐negative results of multiplex NAT among SOT patients with proven cryptococcal meningitis.