Cost‐Effectiveness of a Novel Sleep Intervention in Infancy to Prevent Overweight in Childhood. Issue 11 (3rd October 2020)

• Record Type: Journal Article
• Authors: Tan, Eng Joo; Taylor, Rachael W.; Taylor, Barry J.; Brown, Vicki; Hayes, Alison J.
• Is Part Of: Obesity. Volume 28:Issue 11(2020)
• Page Start: 2201
• Page End: 2208
• Publication Date: 2020-10-03
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.22989
• Languages: English
• ISSNs: 1930-7381

Abstract

Abstract : Objective: The purpose of this study was to determine, from a health funder perspective, whether a sleep intervention, delivered in infancy, either alone or in combination with food, activity, and breastfeeding advice was cost‐effective compared with usual care. Methods: A cost‐effectiveness analysis was conducted alongside the Prevention of Overweight in Infancy (POI) randomized controlled trial for outcomes at 5 years and cost‐effectiveness was modeled to age 15 years using the Early Prevention of Obesity in Childhood microsimulation model. Intervention costs for the Sleep ( n = 192), Combination ( n = 196), and control ( n = 209) groups were determined in 2018 Australian dollars. Incremental cost‐effectiveness ratios (ICERs) were determined for BMI outcomes at 5 and 15 years, with the primary outcome being quality‐adjusted life years (QALYs) modeled over 15 years. Results: The average costs of the Sleep and Combination interventions were $184 and $601 per child, respectively. The ICER for the Sleep intervention was $18, 125 per QALY gained, with a 74% probability of being cost‐effective at a willingness‐to‐pay threshold of $50, 000 per QALY. The ICER for the Combination intervention was $94, 667 per QALY gained with a 23% probability of being cost‐effective. Conclusions: The POI Sleep intervention, without additional advice, was a low‐cost and cost‐effective approach to reducing childhood obesity. Sleep modification programs offer a very promising approach to obesity prevention in children.