A silver-functionalized metal–organic framework with effective antibacterial activity. (9th March 2022)

• Record Type: Journal Article
• Authors: Wu, Ya-Meng; Zhao, Pei-Chen; Jia, Bin; Li, Zhe; Yuan, Shuai; Li, Cheng-Hui
• Is Part Of: New journal of chemistry. Volume 46:Number 13(2022)
• Page Start: 5922
• Page End: 5926
• Publication Date: 2022-03-09
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d1nj06183f
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag(i ) for antibacterial applications. Abstract : Ag nanoparticles have attracted wide research interest due to their broad spectrum of antimicrobial activities. However, Ag nanoparticles are prone to aggregate, which decreases the accessible surface area and diminishes the antibacterial activity. Herein, a metal–organic framework with alkene-functional groups was constructed and postsynthetically modified with Ag(i ) for antibacterial applications. The Ag@Zn-MOF exhibits high antibacterial activity toward E. coli and S. aureus, which reaches ∼100% bacterial reduction at a concentration as low as 25 μgMOF cm −3 (corresponding to 1.7 μgAg cm −3 ). These results demonstrated that Ag(i )-modified MOFs could act as effective antimicrobial agents with potential applications in food and healthcare.