'Awaken' aryl sulfonyl fluoride: a new partner in the Suzuki–Miyaura coupling reaction. (10th February 2022)

• Record Type: Journal Article
• Authors: Zhang, Guofu; Guan, Chenfei; Zhao, Yiyong; Miao, Huihui; Ding, Chengrong
• Is Part Of: New journal of chemistry. Volume 46:Number 8(2022)
• Page Start: 3560
• Page End: 3564
• Publication Date: 2022-02-10
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d1nj05469d
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : An example of the activation of the –SO2 F group, which is traditionally considered a stable group even in the presence of a transition metal, is described using a novel partner in the Suzuki–Miyaura coupling reaction catalyzed by Pd(OAc)2 and Ruphos as ligands. Abstract : An example of the activation of the –SO2 F group, which is traditionally considered a stable group even in the presence of a transition metal, is described using a novel partner in the Suzuki–Miyaura coupling reaction catalyzed by Pd(OAc)2 and Ruphos as ligands. The products showed good to outstanding yields and broad functional group compatibility under optimal conditions. The sequential synthesis of non-symmetric terphenyls and the gram grade process highlight the approach's synthetic utility. DFT calculations have shown that Pd 0 prefers to insert between C–S bonds rather than S–F bonds.