Two new sesquiterpene dimers isolated from the roots of Saussurea lappa (Yunmuxiang). Issue 5 (4th May 2022) - Lai, Sheng-Tian
Abstract: Two new sesquiterpene dimers, lappadimers A and B, were isolated from the roots of Saussurea lappa (Yunmuxiang). Their structures were established on the basis of spectroscopic methods. They were found to have potential anti-inflammatory activity at 10 µ M and could reduce LPS-induced NO levels in murine macrophage, with inhibitory rates of 67% and 47%, respectively. Graphical Abstract: UF0001