The cytoplasmic and extracellular domains of LRP1 promote a convergent mechanism for feedback control of cholesterol synthesis and export, and protect against intracellular cholesterol accumulation. Issue 1 (July 2015) - Boucher, P.; El Asmar, Z.; Jenty, M.; Terrand, J.; Host, L.; Matz, R.; Justiniano, H.; Zerr, A.; Herz, J.; Bruban, V.