MP27-05 EFFICACY AND SAFETY OF DAROLUTAMIDE IN NONMETASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS WITH AND WITHOUT PRIOR LOCAL THERAPY WITH RADICAL PROSTATECTOMY OR RADIOTHERAPY. (May 2022) - Siemens, David Robert; Fizazi, Karim; Shore, Neal D.; Smith, Matthew R.; Ortiz, Jorge; Schmall, Anja; Srinivasan, Shankar; Verholen, Frank; Saar, Matthias