Complexities in diagnosing and treating endophthalmitis in the post stem cell transplant setting. Issue 6 (20th June 2022)

• Record Type: Journal Article
• Authors: Conlon, Peter; Creedon, Margaret; Houlihan, Elaine; O'Rourke, Sadhbh
• Is Part Of: BMJ case reports. Volume 15:Issue 6(2022)
• Publication Date: 2022-06-20
• Subjects: Haematology (incl blood transfusion) -- Infectious diseases -- Ophthalmology; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2022-250552
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Endophthalmitis is a rare but sight-threatening manifestation of systemic infection. Immunosuppression is a well-recognised risk factor for development of endophthalmitis. Determining the aetiology can be complex, particularly in the context of immunosuppression, we present the diagnostic and treatment dilemmas associated with a patient who complains of blurred vision 2 weeks following an allogeneic stem cell transplant for refractory Hodgkin's disease. We demonstrate that in the context of immunosuppression post stem cell transplantation, a broad differential should be maintained until a microbiological diagnosis can be confirmed. In particular, we evaluate how clinical suspicion can diverge from typical fundoscopic findings in the diagnosis of endophthalmitis.