Electrochemiluminescence Single‐cell Analysis on Nanostructured Interface. Issue 6 (3rd August 2021)

• Record Type: Journal Article
• Authors: Zhou, Juanhua; Zhang, Shiyu; Liu, Yang
• Is Part Of: Electroanalysis. Volume 34:Issue 6(2022)
• Page Start: 937
• Page End: 946
• Publication Date: 2021-08-03
• Subjects: electrochemiluminescence -- single-cell analysis -- nanostructured interface; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.202100341
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: Due to the heterogeneity of single cells, the development of single‐cell analysis methods is conducive to the research of cellular mechanisms, clinical diagnosis, and treatment. Electrochemiluminescence (ECL) has the advantage of being controllable in time and space. Compared with spectroscopy, ECL does not require a light source, thus avoiding the interference of scattered light and luminescent impurities. Therefore, ECL is playing an increasingly important role in the field of single‐cell analysis. In ECL single‐cell analysis, it is important to construct a suitable nanostructure interface to realize signal conversion. This review first briefly introduced the ECL system commonly used in single‐cell analysis, then focused on the recent developments in ECL single‐cell analysis on nanostructure interface, finally discussed the future challenges and outlooks of ECL single‐cell analysis. Abstract :