Cancer risk‐reducing surgery: Brazilian society of surgical oncology guideline part 1 (gynecology and breast). Issue 1 (11th June 2022)

• Record Type: Journal Article
• Authors: Carneiro, Vandré Cabral Gomes; Gifoni, Ana Carolina Leite Vieira Costa; Mauro Rossi, Benedito; Andrade, Carlos Eduardo Mattos da Cunha; Lima, Fernanda Teresa de; Galvão, Henrique de Campos Reis; Casali da Rocha, Jose Claudio; Silva Barreto, Leonardo Silveira da; Ashton‐Prolla, Patrícia; Guindalini, Rodrigo Santa Cruz; Farias, Terence Pires de; Andrade, Wesley Pereira; Fernandes, Paulo Henrique de Sousa; Ribeiro, Reitan; Lopes, Andre; Tsunoda, Audrey Tieko; Azevedo, Bruno Roberto Braga; Marins, Carlos Augusto Martinez; Oliveira Uchôa, Diego Nunes de Albuquerque; Dos Santos, Evandro Airton Sordi; Fernández Coimbra, Felipe José; Dias Filho, Francisco Alcides; Lopes, Francisco Carlos de Oliveira; Fernandes, Francisco Guilherme; Ritt, Guilherme Fonteles; Laporte, Gustavo Andreazza; Guimaraes, Gustavo Cardoso; Feitosa e Castro Neto, Heládio; dos Santos, Jocela Cristina; de Carvalho Vilela, Jordana Botelho; Meinhardt Junior, Jorge Guardiola; Cunha, Juliano Rodrigues da; Medeiros Milhomem, Leonardo; da Silva, Luciana Mata; Maciel, Luiza de Freitas; Ramalho, Nathalia Moreira; Leite Nunes, Rafael; Guido de Araújo, Rodrigo; de Assunção Ehrhardt, Rogério; Delgado Bocanegra, Ronald Enrique; Silva Junior, Tyrone Cesar; Oliveira, Viviane Rezende de; Silva Surimã, Walyson; de Melo Melquiades, Miriam; Ribeiro, Heber Salvador de Castro; Oliveira, Alexandre Ferreira;
• Other Names: Rocha Flavio G. guestEditor.; Pinheiro Rodrigo Nascimento guestEditor.; Oliveira Alexandre Ferreira guestEditor.
• Is Part Of: Journal of surgical oncology. Volume 126:Issue 1(2022)
• Page Start: 10
• Page End: 19
• Publication Date: 2022-06-11
• Subjects: breast cancer -- cancer risk‐reducing -- ovarian cancer -- practice guideline -- surgery; Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.26812
• Languages: English
• ISSNs: 0022-4790

Abstract

Abstract: Background: Risk‐reducing operations are an important part of the management of hereditary predisposition to cancer. In selected cases, they can considerably reduce the morbidity and mortality associated with cancer in this population. Objectives: The Brazilian Society of Surgical Oncology (BSSO) developed this guideline to establish national benchmarks for cancer risk‐reducing operations. Methods: The guideline was prepared from May to December 2021 by a multidisciplinary team of experts to discuss the surgical management of cancer predisposition syndromes. Fourteen questions were defined and assigned to expert groups that reviewed the literature and drafted preliminary recommendations. Following a review by the coordinators and a second review by all participants, the groups made final adjustments, classified the level of evidence, and voted on the recommendations. Results: For all questions including risk‐reduction bilateral salpingo‐oophorectomy, hysterectomy, and mastectomy, major agreement was achieved by the participants, always using accessible alternatives. Conclusion: This and its accompanying article represent the first guideline in cancer risk reduction surgery developed by the BSSO, and it should serve as an important reference for the management of families with cancer predisposition.