Fundamentals, biomedical applications and future potential of micro-scale cavitation-a review. Issue 12 (9th May 2022)

• Record Type: Journal Article
• Authors: Seyedmirzaei Sarraf, Seyedali; Rokhsar Talabazar, Farzad; Namli, Ilayda; Maleki, Mohammadamin; Sheibani Aghdam, Araz; Gharib, Ghazaleh; Grishenkov, Dmitry; Ghorbani, Morteza; Koşar, Ali
• Is Part Of: Lab on a chip. Volume 22:Issue 12(2022)
• Page Start: 2237
• Page End: 2258
• Publication Date: 2022-05-09
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/d2lc00169a
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : A fundamental literature review of micro-scale cavitation and its applications for bio-related practices. Abstract : Thanks to the developments in the area of microfluidics, the cavitation-on-a-chip concept enabled researchers to control and closely monitor the cavitation phenomenon in micro-scale. In contrast to conventional scale, where cavitation bubbles are hard to be steered and manipulated, lab-on-a-chip devices provide suitable platforms to conduct smart experiments and design reliable devices to carefully harness the collapse energy of cavitation bubbles in different bio-related and industrial applications. However, bubble behavior deviates to some extent when confined to micro-scale geometries in comparison to macro-scale. Therefore, fundamentals of micro-scale cavitation deserve in-depth investigations. In this review, first we discussed the physics and fundamentals of cavitation induced by tension-based as well as energy deposition-based methods within microfluidic devices and discussed the similarities and differences in micro and macro-scale cavitation. We then covered and discussed recent developments in bio-related applications of micro-scale cavitation chips. Lastly, current challenges and future research directions towards the implementation of micro-scale cavitation phenomenon to emerging applications are presented.