Association of E484K Spike Protein Mutation With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Persons: Maryland, January–May 2021. (2nd September 2021)

• Record Type: Journal Article
• Authors: Feder, Kenneth A; Patel, Ami; Vepachedu, Venkata R; Dominguez, Catherine; Keller, Eric N; Klein, Liore; Kim, Curi; Blood, Tim; Hyun, Judie; Williams, Thelonious W; Feldman, Katherine A; Mostafa, Heba H; Morris, C Paul; Ravel, Jacques; Duwell, Monique; Blythe, David; Myers, Robert
• Is Part Of: Clinical infectious diseases. Volume 74:Number 11(2022)
• Page Start: 2053
• Page End: 2056
• Publication Date: 2021-09-02
• Subjects: COVID-19 -- E484K -- L452R -- B.1.351 -- genomic surveillance; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciab762
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Among 9048 people infected with SARS-CoV-2 between January and May 2021 in Maryland, in regression-adjusted analysis, SARS-CoV-2 viruses carrying the spike protein mutation E484K were disproportionately prevalent among persons infected after full vaccination against COVID-19 compared with infected persons who were not fully vaccinated (aOR, 1.96; 95% CI: 1.36–2.83).