Enteric Illness Outbreaks Reported Through the National Outbreak Reporting System—United States, 2009–2019. (8th September 2021)

• Record Type: Journal Article
• Authors: Wikswo, Mary E; Roberts, Virginia; Marsh, Zachary; Manikonda, Karunya; Gleason, Brigette; Kambhampati, Anita; Mattison, Claire; Calderwood, Laura; Balachandran, Neha; Cardemil, Cristina; Hall, Aron J
• Is Part Of: Clinical infectious diseases. Volume 74:Number 11(2022)
• Page Start: 1906
• Page End: 1913
• Publication Date: 2021-09-08
• Subjects: outbreaks -- enteric illness -- surveillance -- norovirus -- Salmonella; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciab771
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Background: The National Outbreak Reporting System (NORS) captures data on foodborne, waterborne, and enteric illness outbreaks in the United States. This study describes enteric illness outbreaks reported during 11 years of surveillance. Methods: We extracted finalized reports from NORS for outbreaks occurring during 2009–2019. Outbreaks were included if caused by an enteric etiology or if any patients reported diarrhea, vomiting, bloody stools, or unspecified acute gastroenteritis. Results: A total of 38 395 outbreaks met inclusion criteria, increasing from 1932 in 2009 to 3889 in 2019. Outbreaks were most commonly transmitted through person-to-person contact (n = 23 812; 62%) and contaminated food (n = 9234; 24%). Norovirus was the most commonly reported etiology, reported in 22 820 (59%) outbreaks, followed by Salmonella (n = 2449; 6%) and Shigella (n = 1171; 3%). Norovirus outbreaks were significantly larger, with a median of 22 illnesses per outbreak, than outbreaks caused by the other most common outbreak etiologies ( P < .0001, all comparisons). Hospitalization rates were higher in outbreaks caused by Salmonella and Escherichia coli outbreaks (20.9% and 22.8%, respectively) than those caused by norovirus (2%). Case fatality rate was highest in E. coli outbreaks (0.5%) and lowest in Shigella and Campylobacter outbreaks (0.02%). Conclusions: Norovirus caused the most outbreaks and outbreak-associated illness, hospitalizations, and deaths. However, persons in E. coli and Salmonella outbreaks were more likely to be hospitalized or die. Outbreak surveillance through NORS provides the relative contributions of each mode of transmission and etiology for reported enteric illness outbreaks, which can guide targeted interventions. Abstract : Norovirus caused the most outbreaks, illnesses, hospitalizations, and deaths. Persons in Escherichia coli and Salmonella outbreaks were more likely to be hospitalized or die. Outbreak surveillance provides the relative contributions of each transmission mode and etiology and guides targeted interventions.