Long-Term Recording of LTP in Cultured Hippocampal Slices. Issue 4 (2002)
- Record Type:
- Journal Article
- Title:
- Long-Term Recording of LTP in Cultured Hippocampal Slices. Issue 4 (2002)
- Main Title:
- Long-Term Recording of LTP in Cultured Hippocampal Slices
- Authors:
- Shimono, Ken
Baudry, Michel
Ho, Lam
Taketani, Makoto
Lynch, Gary - Abstract:
- Abstract : Long-term potentiation (LTP) was elicited by high frequency stimulation in hippocampal slices cultured on multi-electrode arrays. LTP lasting more than 1 h was recorded in 75% of slices, and a significant number of slices exhibited a non-decaying LTP that lasted more than 48 h. LTP induction was completely and reversibly blocked by an antagonist of the NMDA receptor, APV. Our results suggest the possibility of using chronic recording in hippocampal slices cultured on multi-electrode arrays to study the mechanisms underlying LTP maintenance and stabilization.
- Is Part Of:
- Neural plasticity. Volume 9:Issue 4(2002)
- Journal:
- Neural plasticity
- Issue:
- Volume 9:Issue 4(2002)
- Issue Display:
- Volume 9, Issue 4 (2002)
- Year:
- 2002
- Volume:
- 9
- Issue:
- 4
- Issue Sort Value:
- 2002-0009-0004-0000
- Page Start:
- 249
- Page End:
- 254
- Publication Date:
- 2002
- Subjects:
- Neuroplasticity -- Periodicals
612.82 - Journal URLs:
- https://www.hindawi.com/journals/np/ ↗
- DOI:
- 10.1155/NP.2002.249 ↗
- Languages:
- English
- ISSNs:
- 2090-5904
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 21779.xml