Fabrication of highly bioactive zirconia ceramics via grain‐boundary activation for dental implants. Issue 8 (28th April 2022)

• Record Type: Journal Article
• Authors: Zhang, Wenmin; Ke, Jinhuan; Qian, Guowen; Ye, Jiandong
• Is Part Of: Journal of the American Ceramic Society. Volume 105:Issue 8(2022)
• Page Start: 5069
• Page End: 5081
• Publication Date: 2022-04-28
• Subjects: bioactive glass -- bioactivity -- coating -- dental implant -- grain‐boundary activation -- Y‐TZP -- zirconia; Ceramics -- Periodicals; 620.1405
• DOI: 10.1111/jace.18476
• Languages: English
• ISSNs: 0002-7820

Abstract

Abstract: Yttria‐stabilized tetragonal zirconia polycrystal (Y‐TZP) ceramics with outstanding mechanical properties and aesthetic origins are expected to be used in dental implant applications. However, tetragonal zirconia ceramics are not bioactive, which affect the osseointegration and reliability as dental implant materials. Herein, in this study, Y‐TZP ceramics were modified by grain‐boundary activation via coating a bioactive glass (BG) sol with different content on the crystal surfaces of zirconia powder and followed by being gelled, dried, granulated, low‐temperature treated, molded and sintered at 1450°C for 3 h in air. The effects of BG content on the morphology, phase compositions, mechanical properties, in vitro mineralization ability and cell biological properties of the bioactivity modified Y‐TZP ceramics were evaluated. The BG additive did not affect the tetragonal–monoclinic phase transformation of ZrO2 . However, the addition of BG decreased the flexural strength of the modified Y‐TZP ceramics compared to that of Y‐TZP. The in vitro mineralization results showed that a homogeneous apatite layer was produced on the surface of the Y‐TZP ceramics when they were immersed in the simulated body fluid for 21 days. The cell response results indicated that the bioactive surface modification of Y‐TZP ceramics could promote cell adhesion, propagation and osteogenic differentiation performance. Thus, our research results suggest that the highly bioactive Y‐TZP ceramics could be a potential candidate for dental implant material.