'Hybrid' Bronchopulmonary Malformation – Lobar Emphysema and Extra Lobar Sequestration. (1st June 2022)

• Record Type: Journal Article
• Authors: Vinayak, Thattaruparambil Prakash; Mohanty, Suravi; Das, Kanishka
• Is Part Of: Fetal and pediatric pathology. Volume 41:Number 3(2022)
• Page Start: 505
• Page End: 510
• Publication Date: 2022-06-01
• Subjects: Bronchopulmonary malformation -- hybrid -- emphysema -- sequestration; Pathology, Molecular -- Periodicals; Pediatrics -- Periodicals; Molecular biology -- Periodicals; Pediatric pathology -- Periodicals; Fetal Diseases -- pathology -- Periodicals; Infant, Newborn, Diseases -- pathology -- Periodicals; Pediatrics -- Periodicals; 618.92007
• DOI: 10.1080/15513815.2020.1849474
• Languages: English
• ISSNs: 1551-3815

Abstract

Abstract: Background: Idiopathic lobar emphysema (ILE) and bronchopulmonary sequestration (BPS) are two of the well-characterized pulmonary malformations. Case report: An antenatally detected case of a left bronchopulmonary malformation (BPM) was clinicoradiologically diagnosed to be a left upper lobar emphysema with isolated dextrocardia in the neonatal period. Besides the emphysematous left upper lobe, an accessory lobe akin to an extra lobar BPS was an operative surprise. Histopathological examination of both excised lobes led to a revised diagnosis of a 'hybrid' malformation comprising lobar emphysema and extra lobar BPS. The postoperative recovery was uneventful. Discussion/conclusion: The observations suggest that BPS and ILE may be interim entities in a continuum of abnormal embryogenesis. Such a hybrid malformation has not been hitherto reported.