Ferric metformin drug complex supported on magnetic nanofiber cellulose; An efficient access to 4-H pyrans derivatives and determination of their antimicrobial activity. Issue 7 (3rd April 2022)

• Record Type: Journal Article
• Authors: Matloubi Moghaddam, Firouz; Daneshfar, Maryam; Moghimi, Hamid; Daneshfar, Zahra
• Is Part Of: Synthetic communications. Volume 52:Issue 7(2022)
• Page Start: 974
• Page End: 993
• Publication Date: 2022-04-03
• Subjects: Antibacterial activity -- barbituric acid -- green chemistry -- heterogenic catalyst -- metformin -- organometallic complex; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2022.2056850
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: Magnetic nanofiber cellulose (NFC) was selected as a biopolymer surface for the reaction with ferric metformin and a novel nanocatalyst was prepared. This green heterogeneous organometallic catalyst was analyzed by physiochemical techniques. The new metformin drug complex supported on magnetic NFC was used as a powerful and efficient catalyst for the synthesis of functionalized 4H-pyrans derivatives. The antimicrobial activity of the products showed excellent activity against all the bacterial and fungal strains (especially compounds 7q and 6r ). Graphical Abstract: UF0001