Gait Speed is independently associated with Depression Symptoms in Mild Cognitive Impairment. Issue 4 (4th July 2022)

• Record Type: Journal Article
• Authors: Naharci, Mehmet Ilkin; Katipoglu, Bilal; Veizi, Betul; Tasci, Ilker
• Is Part Of: Aging, neuropsychology, and cognition. Volume 29:Issue 4(2022)
• Page Start: 637
• Page End: 650
• Publication Date: 2022-07-04
• Subjects: Cognition -- dementia -- function -- mood disorders -- older adult; Aging -- Periodicals; Cognition in old age -- Periodicals; Cognition disorders in old age -- Periodicals; Neuropsychology -- Periodicals; Aging -- periodicals; Neuropsychology -- periodicals; Cognition -- periodicals; Mental Disorders -- periodicals; Gerontology -- periodicals; Mental Health -- periodicals; 155.67
• DOI: 10.1080/13825585.2021.1882932
• Languages: English
• ISSNs: 1382-5585

Abstract

ABSTRACT: Depression symptoms are known to influence gait speed in cognitively healthy adults. In this study, we aimed to examine the relationship between gait speed and depression symptoms in older patients with mild cognitive impairment. The participants were classified as slow and normal gait speed based on the Fried criteria. A total of 152 subjects with mild cognitive impairment were included. Of these, 39.5% (n=60) had slow gait speed. Compared to normal speed group (n=92), patients with slow speed had more clinically significant depression (geriatric depression scale score ≥ 6) (p=0.004), cardiovascular disease (p=0.007), recent falls (p<0.001), and anticholinergic burden (p=0.005). Multivariable logistic regression analysis yielded statistically significant associations between slow gait speed and depression in age and gender adjusted [OR:3.30 (1.46-7.46), p=0.004] and fully adjusted [OR: 2.80 (1.10-7.08), p=0.030] models. This study showed an independent association between slow gait speed and depression symptoms in older people with mild cognitive impairment.