A single-molecular ruthenium(ii) complex-based NIR-II fluorophore for enhanced chemo-photothermal therapy. Issue 45 (17th May 2022) - Li, Qianqian
Abstract : Novel NIR-II Ru(ii ) polypyridyl fluorophore Ru-1 dots were designed and synthesized for synergistic chemo-photothermal therapy against 4T1 tumors through the cell apoptosis pathway. Abstract : Novel NIR-II Ru(II) polypyridyl fluorophore Ru-1 dots for synergistic chemo-photothermal therapy against 4T1 tumors were designed and synthesized. Guided by in vivo NIR-II fluorescence imaging, the synergistic therapeutic efficacy, intracellular delivery, and biodistribution of the Ru-1 dots were precisely tracked in real-time.