Engineering analysis of aortic wall stress and root dilatation in the V-shape surgery for treatment of ascending aortic aneurysms. (3rd February 2022)

• Record Type: Journal Article
• Authors: Dong, Hai; Liu, Minliang; Qin, Tongran; Liang, Liang; Ziganshin, Bulat; Ellauzi, Hesham; Zafar, Mohammad; Jang, Sophie; Elefteriades, John; Sun, Wei
• Is Part Of: Interactive cardiovascular and thoracic surgery. Volume 34:Number 6(2022)
• Page Start: 1124
• Page End: 1131
• Publication Date: 2022-02-03
• Subjects: V-shape surgery -- Ascending aneurysm -- Aortic root -- Wall stress -- Finite element analysis; Chest -- Surgery -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.1
• DOI: 10.1093/icvts/ivac004
• Languages: English
• ISSNs: 1569-9293

Abstract

Abstract: OBJECTIVES: The study objective was to evaluate the aortic wall stress and root dilatation before and after the novel V-shape surgery for the treatment of ascending aortic aneurysms and root ectasia. METHODS: Clinical cardiac computed tomography images were obtained for 14 patients [median age, 65 years (range, 33–78); 10 (71%) males] who underwent the V-shape surgery. For 10 of the 14 patients, the computed tomography images of the whole aorta pre- and post-surgery were available, and finite element simulations were performed to obtain the stress distributions of the aortic wall at pre- and post-surgery states. For 6 of the 14 patients, the computed tomography images of the aortic root were available at 2 follow-up time points post-surgery (Post 1, within 4 months after surgery and Post 2, about 20–52 months from Post 1). We analysed the root dilatation post-surgery using change of the effective diameter of the root at the two time points and investigated the relationship between root wall stress and root dilatation. RESULTS: The mean and peak max-principal stresses of the aortic root exhibit a significant reduction, P = 0.002 between pre- and post-surgery for both root mean stress (median among the 10 patients presurgery, 285.46 kPa; post-surgery, 199.46 kPa) and root peak stress (median presurgery, 466.66 kPa; post-surgery, 342.40 kPa). The mean and peak max-principal stresses of the ascending aorta also decrease significantly from pre- to post-surgery, with P = 0.004 for the mean value (median presurgery, 296.48 kPa; post-surgery, 183.87 kPa), and P = 0.002 for the peak value (median presurgery, 449.73 kPa; post-surgery, 282.89 kPa), respectively. The aortic root diameter after the surgery has an average dilatation of 5.01% in total and 2.15%/year. Larger root stress results in larger root dilatation. CONCLUSIONS: This study marks the first biomechanical analysis of the novel V-shape surgery. The study has demonstrated significant reduction in wall stress of the aortic root repaired by the surgery. The root was able to dilate mildly post-surgery. Wall stress could be a critical factor for the dilatation since larger root stress results in larger root dilatation. The dilated aortic root within 4 years after surgery is still much smaller than that of presurgery. Abstract : Ascending aortic aneurysms often include dilatation of the sinotubular junction (STJ) and extend proximally into the root portion of the aorta.