Dantrolene for Generalized Tetanus in Pediatrics: A Case Report and Review of Treatment Options. Issue 4 (3rd July 2022)

• Record Type: Journal Article
• Authors: Khan, Natasha; Zulfiqar, Fizza; Hollander, Leanna; Johnson, Travis; Lamsal, Riwaaj
• Is Part Of: Infectious diseases in clinical practice. Volume 30:Issue 4(2022)
• Publication Date: 2022-07-03
• Subjects: tetanus -- Clostridium tetani -- dantrolene -- vaccine-preventable diseases -- patient comfort; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Periodicals; Electronic journals; 616.9
• DOI: 10.1097/IPC.0000000000001136
• Languages: English
• ISSNs: 1056-9103

Abstract

Abstract: There are only sporadic cases of tetanus in children in the United States. We describe an unimmunized child with generalized tetanus who required nearly a month of mechanical ventilation with analgesia, sedation, and neuromuscular blockade. Dantrolene showed benefit in spasm control and patient comfort when used in combination with other drugs.