Malignant giant cell tumor of toe: A case report and review of literature. Issue 22 (3rd June 2022)

• Record Type: Journal Article
• Authors: Hashimoto, Kazuhiko; Nishimura, Shunji; Ito, Tomohiko; Akagi, Masao
• Is Part Of: Medicine. Volume 101:Issue 22(2022)
• Page Start: e29471
• Publication Date: 2022-06-03
• Subjects: case report -- giant cell tumors -- malignant -- toes; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000029471
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Introduction: A giant cell tumor of soft tissue (GCST) is a benign soft tissue tumor that often occurs subcutaneously in the extremities. Rare cases of malignant GCST have been reported, but its pathogenesis remains unclear. Patients concerns: We report a case of a 68-year-old man who noticed a painless mass on his second toe one and a half years ago. He visited the Department of Dermatology at our hospital. Magnetic resonance imaging revealed a soft tissue tumor, surrounding the distal aspect of the second toe. Diagnosis: A biopsy of the tumor was performed by a dermatologist, and it revealed a malignant giant cell tumor of the toe. Interventions: He was referred to our department and underwent lay amputation for wide-margin resection. Outcomes: No recurrence or metastasis was observed 5 years after treatment. Conclusion: : Malignant GCST should be treated with wide-margin resection immediately after its diagnosis.