How bacteria overcome flagellin pattern recognition in plants. (June 2022)

• Record Type: Journal Article
• Authors: Sanguankiattichai, Nattapong; Buscaill, Pierre; Preston, Gail M.
• Is Part Of: Current opinion in plant biology. Volume 67(2022)
• Publication Date: 2022-06
• Subjects: Flagellin -- FLS2 -- FLS3 -- flg22 -- flgII-28 -- PAMP-Triggered immunity (PTI); Plant molecular biology -- Periodicals; 571.205
• DOI: 10.1016/j.pbi.2022.102224
• Languages: English
• ISSNs: 1369-5266

Abstract

Abstract: Efficient plant immune responses depend on the ability to recognise an invading microbe. The 22-amino acids in the N-terminal domain and the 28-amino acids in the central region of the bacterial flagellin, called flg22 and flgII-28, respectively, are important elicitors of plant immunity. Plant immunity is activated after flg22 or flgII-28 recognition by the plant transmembrane receptors FLS2 or FLS3, respectively. There is strong selective pressure on many plant pathogenic and endophytic bacteria to overcome flagellin-triggered immunity. Here we provide an overview of recent developments in our understanding of the evasion and suppression of flagellin pattern recognition by plant-associated bacteria. Graphical abstract: Image 1 Highlights: Flagellin-triggered immunity relies on functional pattern recognition receptors (PRRs) and their interactors. Bacteria subvert flagellin-triggered immunity before and after flagellin-derived PAMP recognition. Bacteria manipulate flagellin synthesis, structure and degradation to impair PRR activation. Bacteria secrete extracellular and intracellular effectors to suppress flagellin-triggered immune responses.