Association between empathy and drinking among a community sample of heavy drinkers: Sex differences and neural correlates. (September 2022)

• Record Type: Journal Article
• Authors: Robinson, Charles S.H.; Claus, Eric D.; Calhoun, Vince; Swartz, Megan; Fokas, Kathryn; Witkiewitz, Katie
• Is Part Of: Addictive behaviors. Volume 132(2022)
• Publication Date: 2022-09
• Subjects: Alcohol Use Disorder -- Empathy -- Structural MRI -- Gender; Substance abuse -- Periodicals; Alcoholism -- Periodicals; Drug addiction -- Periodicals; Nicotine addiction -- Periodicals; Smoking -- Periodicals; Gambling -- Psychological aspects -- Periodicals; Electronic journals; 362.29
• DOI: 10.1016/j.addbeh.2022.107346
• Languages: English
• ISSNs: 0306-4603

Abstract

Highlights: Previous work suggests individuals with alcohol use disorder show empathy deficits and reductions in gray matter volume. The present study identified structural gray matter correlates in the frontal, temporal, and parietal cortex that were associated with self-reported perspective taking. Self-reported perspective taking was inversely related to alcohol craving for men but not women. Self-reported empathic concern was inversely related to percent heavy drinking days for both men and women. Abstract: Alcohol use disorder (AUD) is a major health problem, yet most individuals with AUD do not perceive a need for formal treatment and do not receive treatment. The lack of treatment seeking among individuals with AUD may suggest a lack of self-awareness and insight into the seriousness of AUD related problems, as well as lack of empathy for the impact of one's drinking on others. Recent work has suggested that empathy may be impaired among individuals seeking treatment for AUD. Further these impairments may differ by sex such that males with lower empathy reported more drinking consequences and greater drinking intensity, but there was no association between empathy and drinking among females. The current study used regression analyses (alpha = 0.05) to examine the association between empathy (as measured by the four scales of the Interpersonal Reactivity Index), independent components of gray matter volume in regions associated with empathy, and drinking variables among non-treatment seeking drinkers with AUD ( N = 136) and also examined these effects by sex. Results showed greater perspective taking was associated with less temporoparietal and frontotemporal gray matter volume (B(SE) = −0.912 (0.043), p = 0.034). An interaction between perspective taking and sex was associated with craving, such that higher perspective taking was associated with less craving for males only (B(SE) = −0.48 (0.243), p = 0.049; R 2 = 0.087). Empathic concern was related to lower percent heavy drinking days for both males and females (B(SE) = −1.57 (0.743), p = 0.035; R 2 = 0.11). The current study found empathy may be an important predictor of craving for males and frequency of heavy drinking for males and females. Future work should investigate whether empathy predicts treatment seeking.